EFFECTIVENESS OF EXISTING METHODS FOR TREATING IMMUNOLOGICAL INFERTILITY
PDF

Ключевые слова

Immunological infertility, Immunosuppression, Antibodies, Spermatozoa, IVF, IUI, Immunotherapy, Anti-sperm antibodies, Sperm washing, Immunoglobulin.

Аннотация

This research paper explores the concept of immunological infertility, its underlying mechanisms, and clinical significance. The main focus is on evaluating the effectiveness of current treatment methods aimed at managing infertility caused by immune system dysfunctions. The study thoroughly reviews pharmacological therapies, such as immunosuppressive drugs and hormonal treatments, alongside assisted reproductive technologies like in vitro fertilization and sperm washing techniques. In addition, experimental and alternative approaches, including immunotherapy and intravenous immunoglobulin (IVIG) treatments, are discussed in terms of their clinical outcomes, benefits, and limitations. The paper emphasizes the importance of accurate diagnosis, the complexity of immune-related infertility cases, and the necessity for personalized treatment strategies. It also outlines challenges in the diagnostic process and highlights potential future directions for research and clinical practice.

This work serves as a valuable resource for medical professionals and researchers involved in reproductive health and immunology.

PDF

Библиографические ссылки

Naz R.K. Immune Infertility: Impact of Immune Reactions on Human Fertility, Contraception, and Pregnancy. – Springer, 2016. – 486 p.

Walsh T.J., Turek P.J. Infertility in the Male. – 5th edition. – Cambridge University Press, 2020. – Chapter 16: Immunologic Infertility. – Pp. 325–340.

IntechOpen (Ed.). IVF Technologies and Infertility. - London: IntechOpen, 2021. – 310 p.

Kutteh W.H., Sacks G. Reproductive Immunology: Basic Concepts and Clinical Applications. – CRC Press, 2020. – 256 p.

Carrell D.T., Peterson C.M. Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice. – Springer, 2010. – 450 p.

Granne, I. (2022). Evidence for the effectiveness of immunologic therapies in women with reproductive failure. Fertility and Sterility, 117(6), 1144–1159.

American Society for Reproductive Medicine (ASRM). (2018). The role of immunotherapy in in vitro fertilization: a guideline. Fertility and Sterility, 110(3), 387–400.

Naz, R.K. (2017). Immune Infertility: Impact of Immune Reactions on Human Fertility, Contraception, and Pregnancy. Springer.

Wolomby-Molondo, J.J. (2024). Male and female immunologic infertility. Geneva Foundation for Medical Education and Research.

Ryzhov, A. (2024). Immunological testing for female infertility: a modern view on the problem. Obstetrics, Gynecology and Reproduction, 18(2), 132–138.

Oribjonov, Otabek. "EARLY DETECTION AND PREVENTION OF RESPIRATORY DISEASES AMONG RESIDENTS OF INDUSTRIAL AREAS THROUGH RADIOLOGICAL IMAGE ANALYSIS." Modern Science and Research 4.4 (2025): 497-499.

Otabek, Oribjonov. "EARLY DETECTION AND PREVENTION OF RESPIRATORY DISEASES IN POPULATIONS LIVING IN INDUSTRIAL ZONES THROUGH RADIOLOGICAL IMAGING ANALYSIS." Web of Medicine: Journal of Medicine, Practice and Nursing 3.4 (2025): 148-149.

Aftab, Maryam, et al. "Recent Trends and Future Directions in 3D Printing of Biocompatible Polymers." Journal of Manufacturing and Materials Processing 9.4 (2025): 129.