MECHANISMS OF DEVELOPMENT AND CONSEQUENCES OF AUTOIMMUNE DISEASES

Аннотация

This paper explores the mechanisms underlying the development and progression of autoimmune diseases. It focuses on the disruption of immune tolerance, the role of genetic and environmental factors, and the molecular pathways involved in autoimmune responses. The paper provides a detailed examination of the immunopathological processes such as T-cell dysfunction, cytokine imbalance, and the generation of autoantibodies. Furthermore, it highlights the clinical manifestations and consequences of various autoimmune conditions, along with current and emerging therapeutic approaches. By analyzing recent scientific findings, the study emphasizes the importance of early diagnosis and personalized treatment in managing these complex disorders. The paper aims to provide a comprehensive overview useful for both clinical and academic audiences interested in the pathophysiology and treatment of autoimmune diseases.