Ключевые слова
Аннотация
Background: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among women of reproductive age. In addition to reproductive dysfunction, PCOS is frequently associated with insulin resistance, hyperandrogenism, obesity, oxidative stress, and persistent low-grade systemic inflammation. Periodontitis is a chronic inflammatory disease of the tooth-supporting tissues in which microbial dysbiosis interacts with an altered host immune-inflammatory response.
Increasing evidence suggests that PCOS and periodontitis may share several biological pathways, including systemic inflammation, impaired metabolic regulation, oxidative stress, and changes in immune responsiveness.
Библиографические ссылки
Papapanou PN, Sanz M, Buduneli N, et al. Periodontitis: Consensus report of Workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. Journal of Periodontology. 2018;89(Suppl 1):S173-S182.
Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. Journal of Periodontology. 2018;89(Suppl 1):S159-S172.
Machado V, Escalda C, Proença L, Mendes JJ, Botelho J. Is there a bidirectional association between polycystic ovarian syndrome and periodontitis? A systematic review and meta-analysis. Journal of Clinical Medicine. 2020;9(6):1961.
Orzeszko R, et al. Association between periodontal diseases and polycystic ovary syndrome: A systematic review. Journal of Clinical Medicine. 2020;9(5):1586.
Bitonti V, Perri T, Cigni L, et al. The association between periodontal disease and polycystic ovary syndrome: A systematic review and meta-analysis. Dentistry Journal. 2025;13(5):188.
Kellesarian SV, Malignaggi VR, Majzoub J, et al. Association of periodontal disease and polycystic ovarian syndrome: A systematic review and meta-analysis with trial sequential analysis. The Open Dentistry Journal. 2019;13:478-487.
Özçaka Ö, Buduneli N, Ceyhan K, et al. Is there an interaction between polycystic ovary syndrome and gingival inflammation? Journal of Periodontology. 2012.
Sharma A, et al. Effect of non-surgical periodontal therapy along with myo-inositol on high-sensitivity C-reactive protein and insulin resistance in women with polycystic ovary syndrome and chronic periodontitis: A randomized controlled trial. Journal of Periodontology. 2017.
European Federation of Periodontology. Guideline on treatment of stage I-III periodontitis. 2020.
European Federation of Periodontology. Evidence-based treatment guidelines for periodontitis.