Аннотация
This study explores the diagnostic significance of the Mixed Antiglobulin Reaction (MAR) test in identifying and treating male immunological infertility. Immunological infertility in men occurs when the body mistakenly produces antibodies against its own sperm cells, impairing their motility, function, and fertilization capability. The MAR test serves as a key diagnostic tool to detect the presence of such anti-sperm antibodies and assess their impact on fertility. The research discusses the mechanism of the MAR test, its application procedures, and how the results influence the choice of treatment strategies. Based on the test outcomes, tailored therapeutic approaches such as immunosuppressive therapy, antioxidant treatment, or assisted reproductive technologies can be recommended. The use of the MAR test enables early detection of immunological factors that contribute to infertility and provides direction for effective, individualized treatment.
Библиографические ссылки
Tüttelmann, F., Ruckert, C., & Röpke, A. (2018). Diagnosis and treatment of male infertility: a review for clinicians. Deutsches Ärzteblatt International, 115(33-34), 571–582.
WHO. (2021). WHO Laboratory Manual for the Examination and Processing of Human Semen (6th ed.). Geneva: World Health Organization.
Francavilla, F., Santucci, R., Barbonetti, A., & Francavilla, S. (2007). Naturally-occurring antisperm antibodies in men: clinical significance and therapeutic approaches. Human Reproduction Update, 13(4), 465–484.
Krapf, J. M., & Sartor, B. M. (2019). Male Immunologic Infertility: Laboratory Diagnosis and Treatment Options. Urologic Clinics of North America, 46(4), 487–500.
Naz, R. K. (2014). Antisperm antibodies: etiology, pathogenesis, diagnosis, and treatment. Fertility and Sterility, 102(1), 17–26.
Kamolova, Nigora. "FAVQULODDA VAZIYATLARDA IJTIMOIY ISHCHILARNING O’RNI." Modern Science and Research 4.4 (2025): 481-484.
Oribjonov, Otabek. "EARLY DETECTION AND PREVENTION OF RESPIRATORY DISEASES AMONG RESIDENTS OF INDUSTRIAL AREAS THROUGH RADIOLOGICAL IMAGE ANALYSIS." Modern Science and Research 4.4 (2025): 497-499.
Otabek, Oribjonov. "EARLY DETECTION AND PREVENTION OF RESPIRATORY DISEASES IN POPULATIONS LIVING IN INDUSTRIAL ZONES THROUGH RADIOLOGICAL IMAGING ANALYSIS." Web of Medicine: Journal of Medicine, Practice and Nursing 3.4 (2025): 148-149.
Aftab, Maryam, et al. "Recent Trends and Future Directions in 3D Printing of Biocompatible Polymers." Journal of Manufacturing and Materials Processing 9.4 (2025): 129.