Ключевые слова
Аннотация
This thesis examines the clinical characteristics of Human Papillomavirus infection in women and the main approaches to its prevention. The clinical course of the infection may vary from an asymptomatic and transient form to persistent infection associated with pathological epithelial changes. Particular attention is given to the importance of early diagnosis, regular screening, identification of high-risk viral types, and assessment of individual risk factors.
Modern preventive approaches, including vaccination, screening, health education, and timely clinical follow-up, are considered. A comprehensive prevention strategy combining these measures may contribute to the early detection of clinically significant changes, reduction of HPV-related complications, and preservation of women’s reproductive health.
Библиографические ссылки
Sung H., Ferlay J., Siegel R.L. et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries // CA: A Cancer Journal for Clinicians. - 2021. - Vol. 71, No. 3. - P. 209–249.
Arbyn M., Weiderpass E., Bruni L. et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis // The Lancet Global Health. - 2020. - Vol. 8, No. 2. - P. 191–203.
Schiffman M., Doorbar J., Wentzensen N. et al. Carcinogenic human papillomavirus infection // Nature Reviews Disease Primers. - 2016. - Vol. 2.
Bosch F.X., Lorincz A., Muñoz N. et al. The causal relation between human papillomavirus and cervical cancer // Journal of Clinical Pathology. - 2002. - Vol. 55, No. 4. - P. 244–265.
Doorbar J., Egawa N., Griffin H. et al. Human papillomavirus molecular biology and disease association // Reviews in Medical Virology. - 2015. - Vol. 25, Suppl. 1. - P. 2–23.
Cohen P.A., Jhingran A., Oaknin A., Denny L. Cervical cancer // The Lancet. - 2019. - Vol. 393, No. 10167. - P. 169–182.