Ключевые слова
Аннотация
Chronic headaches often co-occur with depressive symptoms, affecting quality of life. Functional neuroimaging shows altered activity in prefrontal, cingulate, and limbic regions, while metabolic studies reveal glucose, mitochondrial, and neurotransmitter disturbances. These functional–metabolic changes contribute to pain chronification and emotional dysregulation.
Understanding them is essential for developing targeted therapies and improving patient outcomes.
Библиографические ссылки
Grech, O., Sassani, M., Terwindt, G., Lavery, G., Mollan, S., & Sinclair, A. (2022). Alterations in metabolic flux in migraine and the translational relevance. The Journal of Headache and Pain, 23(1), 127.
Zhao, C., et al. (2024). ^1H MRS reveals abnormal energy metabolism and excitatory inhibitory imbalance in a chronic migraine like state induced by nitroglycerin in mice. The Journal of Headache and Pain, 25, 163.
Абдукадирова, Д. Т., Абдукадиров, У. Т., & Жабборов, А. А. (2022). ДИАБЕТИЧЕСКАЯ ПОЛИНЕЙРОПАТИЯ: ПУТИ ПОЛНОЦЕННОЙ КОРРЕКЦИИ НЕВРОЛОГИЧЕСКОГО ДЕФИЦИТА. Новости образования: Исследование в XXI веке, 306.
Джабборов, А. А. О. (2025, February). ОСОБЕННОСТИ ПОРАЖЕНИЯ ПЕРИФЕРИЧЕСКОЙ НЕРВНОЙ СИСТЕМЫ У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ II ТИПА И АЛГОРИТМ ПРОФИЛАКТИКИ. In Scientific Conference on Multidisciplinary Studies (pp. 158-164).