CLINICAL AND BIOCHEMICAL EVALUATION OF ATRIAL FIBRILLATION RISK IN INDIVIDUALS WITH METABOLIC SYNDROME
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Keywords

Metabolic syndrome, Atrial fibrillation, Risk assessment, CHA2DS2 VASc, Lipid profile, Hemostasis.

Abstract

Metabolic syndrome (MetS) increases the risk of atrial fibrillation (AF). This study assessed 40 patients with MetS and AF to identify risk factors and guide management.

Clinical evaluation included BMI, blood pressure, glucose tolerance, and ECG.

Laboratory tests measured lipid profile and 24-hour urinary catecholamines, and hemostatic parameters were assessed. Risk scores (CHA2DS2‑VASc, CHARGE‑AF, HAS‑BLED) were calculated. Results showed high prevalence of obesity, hypertension, dyslipidemia, and elevated catecholamines. Significant correlations were found between MetS components and AF risk scores. Comprehensive assessment enables targeted interventions to prevent AF development in MetS patients.

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References

Duan C., Zhang W., Shi J., et al. Metabolic score for visceral fat and atrial fibrillation risk: a prospective study. BMC Endocrine Disorders. 2025;25(1):269. doi:10.1186/s12902-025-02083-z.

Rafaqat S., Sharif S., Murad M.A., et al. The Role of Different Components of Metabolic Syndrome in the Pathogenesis of Atrial Fibrillation. Journal of Cardiac Arrhythmias. 2024;37:e1124. doi:10.24207/jca.v37i1.3501.