ELECTROCARDIOGRAPHIC CHANGES IN WOMEN WITH IRON DEFICIENCY ANEMIA: ASSOCIATION WITH HEMOGLOBIN LEVELS
PDF (Русский)

Keywords

Iron deficiency anemia; electrocardiography; hemoglobin; QTc interval; women; cardiovascular changes.

Abstract

Iron deficiency anemia (IDA) is a common condition among women and may lead to cardiovascular dysfunction. This study aimed to evaluate electrocardiographic (ECG) changes in women with IDA and to assess their association with hemoglobin levels. A total of 60 women with IDA underwent laboratory assessment and standard 12-lead ECG recording. Patients were stratified according to anemia severity. ECG abnormalities were identified in 68.3% of cases and increased with decreasing hemoglobin levels. Sinus tachycardia, QTc prolongation, and ST-T changes were significantly more frequent in moderate and severe anemia. Hemoglobin levels showed a significant inverse correlation with heart rate and QTc duration. ECG assessment may be useful for early detection of cardiac involvement in women with iron deficiency anemia.

PDF (Русский)

References

Anker S.D., Colet J.C., Filippatos G., Willenheimer R., Dickstein K., Drexler H. Iron deficiency and cardiovascular disease: clinical relevance and treatment options // European Heart Journal. – 2021. – Vol. 42, № 5. – P. 421–432. – DOI: 10.1093/eurheartj/ehaa886.

Camaschella C. Iron deficiency anemia // New England Journal of Medicine. – 2022. – Vol. 386, № 21. – P. 1981–1992. – DOI: 10.1056/NEJMra2107147.

Sverdlov A.L., Ngo D.T., Chan W.P., Chirkov Y.Y., Horowitz J.D. Impact of iron deficiency on cardiac function and electrophysiology // Journal of the American Heart Association. – 2023. – Vol. 12, № 9. – e028745. – DOI: 10.1161/JAHA.123.028745.