METABOLIK SINDROM VA STRESS HOLATIDAGI ONALARDAN TUGʻILGAN AVLODLAR YURAGIDAGI MORFOLOGIK OʻZGARISHLAR
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Keywords

metabolik sindrom, stress, homiladorlik, avlod, yurak, morfologiya, miokard, prenatal dasturlanish.

Abstract

Ushbu maqolada metabolik sindrom va homiladorlik davridagi stress holatlari natijasida avlodlarning yurak to‘qimalarida yuzaga keladigan morfologik o‘zgarishlar tahlil qilindi. Metabolik sindromga xos bo‘lgan insulin rezistentligi, dislipidemiya, arterial gipertenziya va semirish kabi omillar homila rivojiga salbiy ta’sir ko‘rsatadi. Stress gormonlari (kortizol, katexolaminlar)ning yuqori darajada bo‘lishi esa yurak mushaklarining hujayra darajasida qayta tuzilishiga, mikrosirkulyatsiya buzilishiga va miokardning morfologik zaiflashuviga olib kelishi mumkin. Maqolada onalik organizmidagi patologik omillarning nasl yurak tizimi shakllanishiga ta’siri haqidagi zamonaviy ilmiy ma’lumotlar yoritilgan.

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