Abstract
The modern development of pharmaceutical analysis and medical diagnostics requires the implementation of environmentally safe, sustainable, and highly sensitive analytical methods. In this context, the principles of green chemistry have gained significant importance, as they aim to reduce reagent toxicity, minimize energy consumption, and decrease environmental impact.
One of the most promising approaches is the use of nanoparticle-modified electrodes, which significantly enhance the sensitivity and selectivity of electrochemical sensors. The combination of green synthesis technologies for nanoparticles with electrochemical analytical methods opens new opportunities for the determination of pharmaceutical compounds, biologically active substances, and pharmaceutical pollutants.
The aim of this study is to analyze the potential application of green-synthesized nanoparticles for electrode surface modification in order to improve the efficiency of electrochemical pharmaceutical analysis.
References
Islam, T.; Egyptian et al. (по-авторски «T. Islam, S. …») “Metal Nanoparticles for Electrochemical Sensing” // Sensors (или PMC-NCBI) – 2020. DOI:10.3390/sensors20112755. (PMC)
Białas, K.; et al. “Electrochemical sensors based on metal nanoparticles for pharmaceutical analysis” // Microchimica Acta 2022, Vol. 189, No. 2, Article 122. DOI:10.1007/s00604-022-05252-2. (SpringerLink)
Chaudhary, M.; et al. “Prospects of nanostructure-based electrochemical sensors for analgesic and antipyretic drugs” // Materials Advances (RSC) 2023. DOI:10.1039/d2ma00896c. (pubs.rsc.org)
Mehta, M.; et al. “Recent application of green analytical chemistry: eco-friendly sample preparation, green solvents and sustainable analytical methods” // Future Journal of Pharmaceutical Sciences 2024, 10:58. DOI:10.1186/s43094-024-00658-6. (SpringerOpen)
Tadikonda, R.R.; Afreen, D.; Battula, S. “Green Analytical Chemistry: A Comprehensive Review of Eco-Scale, Greenness Metrics, and Sustainability Approaches” // Journal of Drug Delivery & Therapeutics 2025, Vol. 15, No. 4, pp. 179-182. DOI:10.22270/jddt.v15i4.7089. (jddtonline.info)
Zhu, C.; Yang, W.; Li, H.; et al. “Electrochemical Sensors and Biosensors Based on Nanomaterials” // Analytical Chemistry (ACS) 2015, Vol. 87, No. 1, pp. 230-249. DOI:10.1021/ac5039863. (pubs.acs.org)
Dodevska, T.; et al. “Application of biosynthesized metal nanoparticles in electrochemical sensing” // Journal of the Serbian Chemical Society 2022, Vol. 87, No. 12, pp. 1459-1474. (shd-pub.org.rs)
Хасанова .N. Система образования в Японии и применение педагогических методов в преподавании химии / Общество и инновации/ – 2025. – № 4/S. – С. 392-6. https://doi.org/10.47689/2181-1415-vol6-iss4/S-pp392-396
N. Akhmedova, I. Ortikov, N. Khasanova, K. Zokhidov, K.Turgunov, B. Elmuradov. /Crystal structure of 1-phenyl-1H-pyrazolo [3, 4-d] pyrimidin-4 (5H)-one/ https://doi.org/10.1107/S205698902500934X
Xasanova N., Sullieva S. , Khaydarova D., Radjabov A., Abdullayev D., Normat Kh., Durdiev/Green biosynthesis of copper nanoparticles using citrus fruit extracts for enhanced catalytic and antimicrobial properties/ Procedia Environmental Science, Engineering and Management/ https://www.procedia-esem.eu/pdf/issues/2024/no3/36_Khurramovna_24.pdf