CHRONIC KIDNEY DISEASE (CKD)
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Keywords

Chronic Kidney Disease, CKD, pathophysiology, diagnosis, treatment, complications, prevention, kidney transplantation.

Abstract

Chronic Kidney Disease (CKD) is a progressive condition in which the kidneys gradually lose their function over time, leading to accumulation of toxins, disturbances in fluid-electrolyte balance, and alterations in hematologic and cardiovascular systems. This article provides a detailed overview of the etiology, pathophysiology, clinical manifestations, diagnostic methods, treatment strategies, and complications of CKD. Special attention is given to preventive measures and management approaches in both children and adults. Early detection and appropriate treatment strategies are emphasized as crucial for improving patient quality of life and reducing chronic complications.

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References

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KDIGO Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease, Kidney Int Suppl, 2013.

Nelson Textbook of Pediatrics, 22nd Edition, Elsevier, 2021.

Johnson, R. J., et al. “Chronic Kidney Disease in Children.” Lancet, 2018; 391: 341–356.

National Kidney Foundation. “Kidney Disease Outcomes Quality Initiative (KDOQI) Guidelines,” 2020.